According to a company spokesman, the cuts are related to the sale of the company's Piceance basin subsidiary to Houston-based Terra Energy Partners for $910 million in February.
Employees in WPX's measurement, land, marketing, finance, accounting, human resources and information technology departments are affected.
The company is providing severance benefits and outplacement services.
Following the cuts, WPX will employ about 650 people, compared to 1075 people in September 2015.
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